Aashish Satyajith

Hi! I’m a postdoc at the University of Alberta, advised by Ratmir Derda. I’m working on predicting carbohydrate-protein binding affinities using machine learning models. More broadly I’m interested in obtaining mechanistic, actionable insights in biology using systems modeling and data analysis.

I did my PhD and masters in computer science from Chennai Mathematical Institute. I was advised by Mukund Thattai at NCBS. I studied how the information conveyed by cell-surface carbohydrates (glycans) gets decoded. Take a look at my publications or thesis to know more.

Prior to that, I obtained by B. Tech in Computer Science and Engineering from NIT Calicut.

selected publications

Cell-surface glycans are quantitative reporters of Golgi dysfunction in single cells

Prachi Joshi, Aashish Satyajith, Debiprasad Panda, and 3 more authors

bioRxiv, 2024

Abs DOI Code

Glycans – tree-shaped sugar chains that stick out of eukaryotic cells – perform many functions at the cell surface essentially making multicellularity possible. One of their functions is to convey information about the cell it is on to its surroundings. In this paper, we look at how this information gets decoded by surrounding entities.